• Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study 

      Ricci, Cristian; Wood, Angela; Muller, David; Gunter, Marc J.; Agudo, Antonio; Boeing, Heiner; van der Schouw, Yvonne T.; Warnakula, Samantha; Saieva, Calogero; Spijkerman, Annemieke M.W.; Sluijs, Ivonne; Tjønneland, Anne; Kyrø, Cecilie; Weiderpass, Elisabete; Kühn, Tilman; Kaaks, Rudolf; Sánchez, Maria-Jose; Panico, Salavatore; Agnoli, Claudia; Palli, Domenico; Tumino, Rosario; Engström, Gunnar; Melander, Olle; Bonnet, Fabrice; Boer, Jolanda M.A.; Key, Timothy J.; Travis, Ruth C.; Overvad, Kim; Verschuren, W.M. Monique; Quirós, José Ramón; Trichopoulou, Antonia; Papatesta, Eleni-Maria; Peppa, Eleni; Iribas, Conchi Moreno; Gavrila, Diana; Forslund, Ann-Sofie; Jansson, Jan-Håkan; Matullo, Giuseppe; Arriola, Larraitz; Freisling, Heinz; Lassale, Camille; Tzoulaki, Ioanna; Sharp, Stephen J.; Forouhi, Nita G.; Langenberg, Claudia; Saracci, Rodolfo; Sweeting, Michael; Brennan, Paul; Butterworth, Adam S.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-29)
      Objective To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke.<p> <p>Design Multicentre case-cohort study.<p> <p>Setting A study of cardiovascular disease (CVD) determinants within the European Prospective Investigation into Cancer and nutrition cohort (EPIC-CVD) from eight European ...
    • Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study 

      Perrier, Flavie; Viallon, Vivian; Ambatipudi, Srikant; Ghantous, Akram; Cuenin, Cyrille; Hernandez-Vargas, Hector; Chajès, Véronique; Baglietto, Laura; Matejcic, Marco; Moreno-Macías, Hortensia; Kühn, Tilman; Boeing, Heiner; Karakatsani, Anna; Kotanidou, Anastasia; Trichopoulou, Antonia; Sieri, Sabina; Panico, Salvatore; Fasanelli, Francesca; Dollé, Martijn; Onland-Moret, Charlotte; Sluijs, Ivonne; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Huerta, José María; Ardanaz, Eva; Dorronsoro, Miren; Tong, Tammy Y.N.; Tsilidis, Konstantinos K.; Riboli, Elio; Gunter, Mark J.; Herceg, Zdenko; Ferrari, Pietro; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-02)
      <i>Background</i> - There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the association of dietary folate and alcohol intake on leukocyte DNA methylation levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) ...
    • Consumption of meat, fish, dairy products, and eggs and risk of ischemic heart disease: A prospective study of 7198 incident cases among 409 885 participants in the Pan-European EPIC Cohort 

      Key, Timothy J.; Appleby, Paul N.; Bradbury, Kathryn E.; Sweeting, Michael; Wood, Angela; Johansson, Ingegerd; Kühn, Tilman; Steur, Marinka; Weiderpass, Elisabete; Wennberg, Maria; Würtz, Anne Mette Lund; Agudo, Antonio; Andersson, Jonas; Arriola, Larraitz; Boeing, Heiner; Boer, Jolanda M.A.; Bonnet, Fabrice; Boutron-Ruault, Marie-Christine; Cross, Amanda J.; Ericson, Ulrika; Fagherazzi, Guy; Ferrari, Pietro; Gunter, Marc; Huerta, José María; Katzke, Verena; Khaw, Kay-Tee; Krogh, Vittorio; La Vecchia, Carlo; Matullo, Giuseppe; Moreno-Iribas, Conchi; Naska, Androniki; Nilsson, Lena Maria; Olsen, Anja; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Molina-Portillo, Elena; Quirós, J. Ramón; Skeie, Guri; Sluijs, Ivonne; Sonestedt, Emily; Stepien, Magdalena; Tjønneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; Tzoulaki, Ioanna; van der Schouw, Yvonne T.; Verschuren, W.M. Monique; di Angelantonio, Emanuele; Langenberg, Claudia; Forouhi, Nita; Wareham, Nick; Butterworth, Adam; Riboli, Elio; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-22)
      <i>Background</i> - There is uncertainty about the relevance of animal foods to the pathogenesis of ischemic heart disease (IHD). We examined meat, fish, dairy products, and eggs and risk for IHD in the pan-European EPIC cohort (European Prospective Investigation Into Cancer and Nutrition).<P><P> <i>Methods</i> - In this prospective study of 409 885 men and women in 9 European countries, diet ...
    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...
    • Isocaloric substitution of carbohydrates with protein: The association with weight change and mortality among patients with type 2 diabetes 

      Campmans-Kuijpers, Marjo J.E.; Sluijs, Ivonne; Nöthlings, Ute; Freisling, Heinz; Overvad, Kim; Weiderpass, Elisabete; Fagherazzi, Guy; Kühn, Tilman; Katzke, Verena A.; Mattiello, Amalia; Sonestedt, Emily; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Spijkerman, Annemieke M.W.; Barricarte, Aurelio; Ricceri, Fulvio; Chamosa, Saioa; Johansson, Ingegerd; Winkvist, Anna; Tjønneland, Anne; Sluik, Diewertje; Boeing, Heiner; Beulens, Joline W.J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-18)
      Background: The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD) mortality risk in patients with type 2 diabetes. <p>Methods: The study ...
    • Plant foods, dietary fibre and risk of ischaemic heart disease in the European prospective investigation into cancer and nutrition (EPIC) cohort 

      Perez-Cornago, Aurora; Crowe, Francesca L; Appleby, Paul N; Bradbury, Kathryn E; Wood, Angela M.; Jakobsen, Marianne Uhre; Johnson, Laura; Sacerdote, Carlotta; Steur, Marinka; Weiderpass, Elisabete; Würtz, Anne Mette L; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Karakatsani, Anna; Vecchia, Carlo La; Masala, Giovanna; Tumino, Rosario; Panico, Salvatore; Sluijs, Ivonne; Skeie, Guri; Imaz, Liher; Petrova, Dafina; Ramón Quirós, J; Yohar, Sandra Milena Colorado; Jakszyn, Paula; Melander, Olle; Sonestedt, Emily; Andersson, Jonas; Wennberg, Maria; Aune, Dagfinn; Riboli, Elio; Schulze, Matthias B; di Angelantonio, Emanuele; Wareham, Nicholas J; Danesh, John; Forouhi, Nita G; Butterworth, Adam S; Key, Timothy J (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-27)
      <i>Background</i> - Epidemiological evidence indicates that diets rich in plant foods are associated with a lower risk of ischaemic heart disease (IHD), but there is sparse information on fruit and vegetable subtypes and sources of dietary fibre. This study examined the associations of major plant foods, their subtypes and dietary fibre with risk of IHD in the European Prospective Investigation into ...